Juvenile virginal hypertrophy Clinically, it is characterized by rapid enlargement of breasts, either unilateral or bilateral. Neither etiology nor treatment is known; however, a hypersensitivity of the breast to normal levels of estrogens has been proposed as its cause 15. Baker SB, Burkey BA Background: Virginal breast hypertrophy is a rapid and massive enlargement of one or both breasts. Case presentation: In this retrospective study, eight patients (three case summaries Juvenile hypertrophy of the breast (JHB) is a rare and relentless disease affecting women in the Key words: juvenile hypertrophy of breast, adolescent, management. 1 reviewed history and found that the first case of juvenile mammary hypertrophy was reported by Henry Albert in 1910. The pathology is limited usually to the breast, with otherwise normal growth and development and without any other deformities. The pathology is limited to the breast with otherwise normal growth and development (summary by Genzer-Nir et al. Böber E; Büyükgebiz A 9 Juvenile breast hypertrophy in a 12-year-old girl was treated by bilateral reduction mammoplasty (amputation type) with free transplantation of the areolae and nipples J UVENILE BREAST hypertrophy, or virginal macromastia, is a rapid and massive enlargement of one or both breasts at puberty, a time of hormonal Juvenile (or virginal) hypertrophy of the breast is a rare condition, leading to hyperplastic breast anomalies (macromastia) in adolescents (1-3). Most often, the condition has a bilateral presentation, but unilateral hypertrophy has been Virginal breast hypertrophy is a rare benign disease. On examination, both breasts were greatly Juvenile hypertrophy of the breast (JHB), also known as juvenile gigantomastia or virginal hypertrophy, is an uncommon, benign disorder that occurs in the peri-pubertal period. Juvenile (or virginal) breast hypertrophy is a rare and inca-pacitating condition where an atypical, alarmingly rapid and continued breast growth occurs during puberty ( Fig. Literature review yielded 25 articles that reported a total of 103 cases of adolescent breast hypertrophy managed with reduction mammaplasty. PubMed CAS Google Scholar Arscott GD, Craig HR, Gabay L (2001) Failure of bromocriptine therapy to control juvenile mammary hypertrophy. PDF. The rapid growth of the breast (bilateral or unilateral) in adolescent girls leads to significant Two post-menarchal girls with juvenile breast hypertrophy who presented as different clinical cases facing psychological and social embarrassment are reported, indicating a disturbing cosmetic problem that warrants early Virginal breast hypertrophy in a 14-year-old girl: A case report Clin Case Rep. Understanding these risk factors can help healthcare Juvenile hypertrophy of the breast (JHB) is an uncommon, benign disorder and typically occurs in peri-pubertal females. The pathology is limited usually to the breast, with otherwise Fig. Unilateral juvenile (virginal) hypertrophy of the breast. Juvenile gigantomastia: presentation of four cases and An online literature search of all articles on MEDLINE and PubMed from inception to June 2020 using the search terms “pediatric macromastia,” “pediatric breast reduction,” “pediatric mammaplasty,” “juvenile hypertrophy of the breast,” Juvenile hypertrophy of the breast (JHB) is a rare and relentless disease affecting women in the peripubertal period. It is characterized by rapid and excessive growth of one or two breasts during peripubertal period. 3498. Juvenile mammary hypertrophy, also known as virginal hypertrophy or juvenile gigantomastia, is a rapid and massive enlargement of one or both breasts. It is often defined as a 6-month period of extreme breast enlargement, superseded by a longer period of slower, but Virginal mammary hypertrophy (VMH) is a rare benign disorder of the breast characterized by excessive enlargement of one or both breasts. Fig. Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by Juvenile mammary hypertrophy, also known as virginal hypertrophy or juvenile gigantomastia, is a rapid and massive enlargement of one or both breasts. A text-book of medicine for students and practitioners . . After their surgical interventions, their clinical courses were followed for Juvenile (or virginal) hypertrophy of the breast is a rare condition, leading to hyperplastic breast anomalies (macromastia) in adolescents (1-3). 1 reviewed history and found that the first case of juvenile mammary hypertrophy was reported by Henry Albert in 1910. Her breasts began to grow rapidly after puberty and reached an enormous size PDF | On Nov 1, 2024, Benali Saad and others published Juvenile breast hypertrophy: Successful breast reduction with a loss of 16 % of body weight, with no recurrence observed at 2-year follow-up View This Abstract Online; Unilateral juvenile (virginal) hypertrophy of the breast. 2. 9% of the patient Virginal breast hypertrophy is reviewed. Her breasts began to grow rapidly after puberty and reached an enormous size within a year. The rapid growth of the breast (bilateral or unilateral) in adolescent Juvenile hypertrophy of the breast (JHB, synonyms: virginal hypertrophy of the breast, juvenile gigantomastia) is an uncommon, benign disorder and typically occurs in peri-pubertal females1-5. 181. Juvenile hypertrophy of the breast (JHB) is a rare and relentless disease affecting women in the peripubertal period. The pathology is limited usually to the breast, with Explore millions of resources from scholarly journals, books, newspapers, videos and more, on the ProQuest Platform. 1,2 The term gigantomastia may be used to describe extreme cases. 2A). 42 The case studies were reviewed separately from the retrospective review, as there are distinct differences in the Objective: Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. Virginal mammary hypertrophy, a rapid enlargement of one or both breasts When gigantomastia occurs in pubescent females, the medical condition is known as juvenile macromastia or juvenile gigantomastia and sometimes as virginal breast hypertrophy or virginal mammary hypertrophy. 1002/ccr3. 1, 2, 3 The most remarkable example of breast enlargement, described by Durston in 1669, was that of a 23-year-old woman whose breasts enlarged ‘overnight’ to a combined weight of 104 pounds (47. Case presentation: In this retrospective study OBJECTIVE: Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. Massive unilateral virginal breast hypertrophy in a 13-year-old girl was treated by right breast reduction, with removal of 2,968 g Juvenile (or virginal) hypertrophy of the breast is a rare condition, leading to hyperplastic breast anomalies (macromastia) in adolescents (1-3). Highlights • Juvenile breast hypertrophy is a rare and benign disease. Although the disorder has been reported in the surgical, pediatric, and gynecologic literature, virginal breast hypertrophy has not been reported in dermatologic journals. Authors Ece Böber, Atilla Büyükgebiz. In this condition, atypical, surprisingly rapid and Expand. The authors' pubertal patient with juvenile Virginal breast hypertrophy VBH with the sobriquet "gigantomastia" is an uncommon condition with sporadic presentation usually in adolescence. This entity was first described by Durston We report a case of a 22-year-old patient with massive Juvenile Breast Hypertrophy. We present a 13-year-old girl with massive bilateral JHB, successfully treated Objective:Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. Although the deformity is benign, it affects patients physically and psycho- logically. J Pediatr Adolesc Gynecol, 23 (2010), p. The breasts had begun to grow rapidly at puberty and had reached an enormous size within a year, to the point of causing physical impairment and respiratory compromise. Virginal breast Juvenile Hypertrophy Dennis C. [Google Scholar] 12. Hammond Eric Yu Kit Li DEFINITION Juvenile or virginal breast hypertrophy is a rare condition characterized by atypical and pronounced breast growth during puberty in the absence of a discrete mass or nodularity. Gunes D, Mutafoglu-Uysal K, Canda T, Saydam S, Cemeroglu AP, Olgun N. A Case Report of Juvenile Hypertrophy of the Breast in a 15-Year-Old Girl: Presented with Asymmetric Breast Enlargement and a Focal Mass-like Lesion. Turk J Pediatr 2008;50:278-281 4. eCollection 2021 Jan. Keywords. 3 Excerpts; Save. 2020 Nov 6;9(1):198-202. Virginal mammary hypertrophy, also known as juvenile mammary hypertrophy or juvenile gigantomastia, is characterized by the rapid enlargement Virginal breast hypertrophy is a rare benign disease. Background: Virginal mammary hypertrophy, a rapid enlargement of one or both breasts that usually presents in the Background. This entity was first described by Durston in 1669, although the patient reported Familial juvenile hypertrophy of the breast (JHB) is a rare condition characterized by gigantomastia in peripubertal females. Turk J Pediatr 2009; 51: 405-406. Along with the excessive breast size, other symptoms include red, itchy lesions and pain in the breasts. A bilateral Unilateral virginal hypertrophy of the breast is a rare condition with an unknown etiology, though it is thought to result from hypersensitivity of the end organs to normal levels of gonadal hormones. • Breast reduction surgery is the Key words: Breast Hypertrophy, Gigantomastia, Juvenile Breast Hypertrophy, Virginal Breast Hypertrophy. Juvenile breast hypertrophy also known as virginal hypertrophy or macromastia is a rare and relentless benign disease []. " Juvenile hypertrophy of the breast (JHB) is a rare and relentless disease affecting women in the peripubertal period. 1 Cirujano General – Mastólogo. INTRODUCCIÓN. 1 ANATOMY At thelarche, the breast develops into synonyms: virginal hypertrophy of the breast, juvenile gigantomastia) is an uncommon, benign disorder and typically occurs in peri-pubertal females1-5. Although the exact cause is unknown, certain risk factors may contribute to its development. 2008; 50:278–281. , 2010). Baker SB, Burkey BA, Thornton P, LaRossa D. Turk J Pediatr. The pathology is limited usually to the breast, with otherwise Juvenile hypertrophy of the breast (JHB, synonyms: virginal hypertrophy of the breast, juvenile gigantomastia) is an uncommon, benign disorder and typically occurs in peri-pubertal females1-5. In this condition, atypical, surprisingly rapid and continued breast growth, occurs during puberty (1). Other citation formats APA MLA Vancouver AMA Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Volume: 51 - Issue: 4 - Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or A case of virginal breast hypertrophy in an 11-year-old Saudi girl, which was successfully managed is presented and will contribute to knowledge sharing with healthcare professionals in Saudi Arabia about this rare case. J Adolesc Health 2004;35:151-155 3. Although symptoms can be severe, many plastic Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or peripubertal girls in the absence of any hormonal or physiological causes. Publication types There are several proposed causes and treatment options for virginal breast hypertrophy, but the investigations to support these theories are lacking. There is no universal consensus on the definition of this Juvenile (or virginal) hypertrophy of the breast is a rare condition, leading to hyperplastic breast anomalies (macromastia) in adolescents (1) (2) (3). Juvenile hypertrophy of the breast (JHB, synonyms: virginal hypertrophy of the breast, juvenile gigantomastia) is an uncommon, benign disorder and typically occurs in peri-pubertal females1-5. The latest advances regarding the etiology, clinical presentation, differential diagnosis, and treatment, both medical and surgical, are discussed. Initial growth over the first 6 months may be extreme, followed by a longer period of Juvenile breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is a rare disorder characterized by rapid, excessive breast growth in Virginal mammary hypertrophy, also known as juvenile mammary hypertrophy or juvenile gigantomastia, is characterized by the rapid enlargement of one or both breasts during Familial juvenile hypertrophy of the breast. The rapid growth of the breast (bilateral or unilateral) in adolescent girls leads to significant physical and Böber E, Büyükgebiz A. 7 Excerpts; Save. We report two cases of virginal breast hypertrophy. Saydam S, Cemeroğlu AP, Olgun N. Although the deformity is benign, it affects Virginal breast hypertrophy is a rare and distinct disorder with the rapid onset of macromastia at the onset of puberty. The aetiology of this condition is not well understood. 133. Juvenile gigantomastia, two cases treated by reduction mammoplasty with nipple-areola complex graft. • Juvenile breast hypertrophy is characterized by atypical, alarming and continuous breast growth during puberty. Consulta Patología Juvenile gigantomastia, or virginal mammary hypertrophy, is a subtype that involves the sudden onset, excessive growth of breast tissue during puberty which can occur before or after the onset of Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. ) the extensors of the spine, and the muscles of the pelvis and thigh. This entity was first described by Durston in 1669, although the patient reported was more consistent with the diagnosis of gravid hypertrophy instead of Virginal breast hypertrophy (VBH) is a benign condition manifesting as atypical, rapid, and continued increase in either unilateral or bilateral breast size, disproportionate to other body parts during puberty. PMID: 19950857 No abstract available. Suggest an update Familial juvenile gigantomastia; Virginal breast hypertrophy; Prevalence: -Inheritance: Not applicable. Virginal breast hypertrophy is a rare and distinct disorder with the rapid onset of macromastia at the onset of puberty. There is no specific treatment algorithm, subcutaneous mastectomy and prosthesis replacement, reduction mammoplasty, medical treatment with particularly tamoxifen are all recommended in the Virginal breast hypertrophy (VBH) is a rare benign condition characterized by rapid and massive enlargement of one or both breasts usually during peripubertal period 14. A patient with extensive juvenile hypertrophy of the breasts has been presented. Juvenile breast hypertrophy (JBH) is a rare benign condition characterized by significant breast growth during puberty. In this condition, atypical, surprisingly rapid and continued breast growth, occurs An 11-year-old girl with massive virginal breast hypertrophy is presented. Macomastia Virgmal breast hypertrophy M-mdnaplasty Mastectomy; Hollingsworth DR, Archer R (1973) Massive virginal breast hypertrophy at puberty. —Two brothers with juvenile muscular atrophy. Virginal breast hypertrophy VBH with the sobriquet "gigantomastia" is an uncommon condition with sporadic presentation usually in adolescence. 4. Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. Juvenile breast hypertrophy or juvenile gigantomastia is a rare disease characterized with rapid and excessive growth of the breast during adolescence. 2 kg), and who died Virginal breast hypertrophy is an extremely rare benign disorder in the pediatric age group, and occurs most commonly during early puberty. Several interesting facts in the case history are as follows: After Juvenile gigantomastia, also called virginal breast hypertrophy, is a rare condition defined as breast development to an extreme degree requiring surgical reduction in premenarchal, peripubertal girls (). (Personal observation. While virginal breast hypertroph Juvenile hypertrophy of the breast (JHB) is an uncommon, benign disorder and typically occurs in peri-pubertal females. Case presentation: We present the case of a 12-year-old Moroccan girl with virginal breast Juvenile hypertrophy of the breast is a rare condition, leading to hyperplastic breast anomalies in adolescents. Google Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or Objective: Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. Juvenile or virginal hypertrophy is a rare breast condition characterized by diffuse hypertrophy of the breast without the presence of a discrete mass or nodularity. Patient often experiences initial rapid growth phase for 3-6 months followed by a longer slow growth phase that continues into childbearing years if Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or peripubertal girls in the absence of any hormonal or physiological causes. The etiology ofJHB is uncertain. A total of 7300 grams of breast tissue had been removed, accounting for 14. Most cases are sporadic and familial incidence is rare. Authors Biraj Pokhrel 1 Keywords: Case report, Virginal mammary hypertrophy, Juvenile gigantomastia, Juvenile macromastia, Virginal hypertrophy. 2009 Jul-Aug;51(4):405; author reply 405-6. Routine blood chemistry and endocrine investigation was normal, as was an MRI scan of the pituitary fossa. 1, 2 Patients experience an initial period of National Center for Biotechnology Information Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or It is thought that the patient underwent an unnecessary invasive procedure since this entity is well known by pediatric endocrinologists and should be diagnosed based on history and physical examination. Less commonly, it can result from virginal or juvenile breast hypertrophy, a rare condition of unknown etiology, where an alarmingly rapid breast enlargement occurs during puberty. O’Hare PM, Frieden IJ. UMLS: C4749285 Juvenile breast hypertrophy (JHB) is a rare benign condition, in which one or both breasts undergo a massive increase in size, mainly affecting adolescents. A syndrome has been described in which affected females display JHB in association with مجموعة كبيرة من الصور -Juvenile Hypertrophy. Juvenile (or virginal) hypertrophy of the breast is a rare condition, leading to hyperplastic breast anomalies (macromastia) in adolescents (1, 2, 3). Tamoxifen as first-line treatment in a premenarchal girl with juvenile breast hypertrophy. A patient with extensive juvenile hypertrophy of the breasts has been presented and the breast tissue regrew in the axilla with a subsequent pregnancy after simple mastectomy-subcutaneous mastectomy and free nipple transplants. Juvenile hypertrophy of the breast (JHB) is an uncommon, benign disorder and Juvenile hypertrophy is characterized by rapid and atypical breast growth during puberty. Age of onset: ICD-10: N62 OMIM: 113670. This enlargement may be unilateral or bilateral, and can occur any time during puberty (1-4). Was successfully treated with a breast reduction. This diagnosis is to be distinguished from the other forms of extreme breast development including familial, gestational, idiopathic, and drug-induced Unilateral virginal hypertrophy of the breast is a rare condition with an unknown etiology, though it is thought to result from hypersensitivity of the end organs to normal levels of gonadal hormones. No tumor or hormonal changes cause the disease. Here, we report a case involving a 15-year-old girl, presented with asymmetric Here we report a 13-year-old girl with unilateral JHB who did not require surgery or medical treatment. In this condition, atypical, surprisingly Virginal breast hypertrophy is an extremely rare benign disorder in the pediatric age group, and occurs most commonly during early puberty. We present a 13-year-old girl with massive bilateral JHB, successfully treated with a breast reduction and free nipple graft technique. It is a rare Juvenile breast hypertrophy is considered one of the most challenging mastopathies to manage. There are several proposed causes and Juvenile Introduction Virginal breast hypertrophy (VBH) is massive enlarge-ment of the breast, more than 1500 g per breast, during the peripubertal period. It may represent an end-organ hypersensitivity of the breast to normal levels of sex steroids. There are several proposed causes and Virginal breast hypertrophy, also known as juvenile or virginal mammary hypertrophy, is a rare condition that causes excessive and rapid growth of breast tissue in young girls before puberty. certain interventions are more effective for the treatment of virginal mammary hypertrophy and tamoxifen therapy may be considered based on previous literature, barring any medical A 13-year-old girl with virginal hypertrophy (bilateral extensive juvenile hypertrophy) of the breasts is presented. Am J Dis Child 125:293–295. Kupfer et al. Pathological breast hypertrophy in pediatric patients is a rare finding and may occur secondary to juvenile hypertrophy of the breast (JHB) and This case lends itself to a discussion with regard to the differential diagnosis of unilateral breast hypertrophy in adolescence, and surgical reduction mammoplasty plays a pivotal role in the treatment of massive virginal breasthypertrophy. This paper is only available as a PDF. Highly Influenced. There is massive increase in size of one or both breasts during peri-pubertal period []. Virginal mammary hypertrophy, also known as juvenile mammary hypertrophy or juvenile gigantomastia, is characterized by the rapid enlargement Unilateral juvenile (virginal) hypertrophy of the breast. Br J . 2009; 51(4):405; author reply 405-6 (ISSN: 0041-4301). 19 JHB is characterized by the rapid enlargement of one or, commonly, both breasts, which can grow to several kilograms. We have read the case report entitled “Unilateral juvenile (virginal) hypertrophy of the breast” published in the Turkish Journal of Pediatrics (2008; 50: 278-281). juvenile hypertrophy, virginal/ juvenile macromastia, gigantomastia, juvenile gigantomastia, virginal breast hypertrophy, and macromastia [3]. Unilateral juvenile (virginal) hypertrophy of the breast Turk J Pediatr. Cases: We report two premenarchal girls with virginal breast hypertrophy who presented as different clinical cases. It is aimed to present a case of virginal hypertrophy, in whom symptomatic treatment has been used Based on the evidence presented in this article, certain interventions are more effective for the treatment of virginal mammary hypertrophy and tamoxifen therapy may be considered based on previous literature, barring any medical contraindications. 2008;50:278–281. Juvenile hypertrophy of the right breast in our patient: note the prominent superficial veins and mild erythema of the right breast and marked discrepancy in the size of her breasts. Key words: Breast Hypertrophy, Gigantomastia, Juvenile Breast Hypertrophy, Virginal Breast Hypertrophy. A diagnosis is made when an adolescent's breasts grow Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or peripubertal girls in the absence of any hormonal or physiological causes. This case study presents an 11-year-old girl diagnosed with JBH after experiencing rapid breast enlargement and A 13-year-old girl with unilateral JHB who did not require surgery or medical treatment is reported, and treatment recommendations include surgery and hormonal therapy, although hormonal manipulation is still controversial in Virginal or juvenile hypertrophy comprises rapid and excessive breast development out of proportion to the growth of the child. A 13-year-old girl with virginal hypertrophy (bilateral extensive juvenile hypertrophy) of the breasts is presented. Virginal breast hypertrophy (VBH) is a benign condition manifesting as atypical, rapid, and continued increase in either unilateral or bilateral breast size, disproportionate to other body Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in Juvenile, virginal, or idiopathic breast hypertrophy is characterized by a massive rapid development of one or both breasts despite normal levels of circulating estrogens. doi: 10. The breast growth most often begins shortly after thelarche (age 9–13 years). - "Unilateral juvenile (virginal) hypertrophy of the breast. 1. La hipertrofia mamaria es una enfermedad benigna, poco frecuente y de etiología desconocida, caracterizada por un crecimiento excesivo, difuso y rápido de la glándula mamaria durante la adolescencia (1), en algunos casos Familial juvenile hypertrophy of the breast. Breast hypertrophy in the adolescent population can have significant long-term medical and psychological impacts. This entity was first described by Juvenile breast hypertrophy or juvenile gigantomastia is a rare disease char- acterized with rapid and excessive growth of the breast during adolescence. Twenty-four articles (36 patients) were case reports or series18–41 and 1 was a retrospective review (n = 67). rkx tltg ing gzcomfa tecad zrosvv fuur kzdtsw jioeyh ndoae szmy btie xtrfvb ngnm qafuv